Miquel Castellote will defend his PhD thesis on 27 November 2025
The PhD researcher Miquel Castellote from the DBCI group at ICMAB-CSIC, will defend his PhD thesis on Thursday, 27 November 2025 at ICMAB.
3D biohybrid hydrogels as artificial extracellular matrix for CAR T cell and organoid culture
PhD Candidate: Miquel Castellote
Date: Thursday, 27 November 2025 Time: 11.00 AM Venue: Sala d'Actes Carles Miravitlles
Abstract
This thesis describes the development of novel biohybrid hydrogels consisting of poly(ethylene glycol) – heparin as artificial extracellular matrices for applications in immunotherapy and cancer modelling. In particular, we focused on improving the ex vivo manufacture of CAR T cell products for cancer immunotherapy, and the establishment of both hematological and solid cancer organoid (tumoroid) models.
Supervisor
Judith Guach Camell, ICMAB-CSIC
PhD Committee
President: Carles Mas Moruno, UPC, Spain
Secretary: Julia Lorenzo Rivera, UAB, Spain
Vocal: Enrique Javier Arenas Lahuerta, Josep Carerras Leukaemia Research Institute, Spain
University: Universitat Autònoma de Barcelona (UAB)
